Browsing by Author "Espinoza, Omar"
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- ItemHigh exposure to boron in drinking water and sperm parameters in Chilean young people(2017) Cortés Arancibia, Sandra; Ferreccio Readi, Catterina; Espinoza, Omar
- ItemStudies on quinones. Part 40 : Synthesis and cytotoxicity evaluation of anthraquinone epoxides and isomerization products(2006) Valderrama Guerrero, Jaime Adolfo; Espinoza, Omar; González, M. Florencia; Tapia Apati, Ricardo; Rodríguez, Jaime A.; Theoduloz, Cristina; Schmeda Hirschmann, G.
- ItemSynthesis and Antitumor Evaluation of Thiophene Analogs of Kigelinone(BENTHAM SCIENCE PUBL LTD, 2009) Valderrama, Jaime A.; Espinoza, Omar; Rodriguez, Jaime; Theoduloz, CristinaThe synthesis of kigelinone thiophene analogs and related naphtho[2,3-b] thiophene-4,9-quinones from 2-substituted 4,7-dimethoxybenzo[b]thiophenes via an oxidative deprotection, Diels-Alder, and oxidative aromatization reaction sequence is reported. The 2-substituted naphtho[2,3-b] thiophene-4,9-quinones display significant antitumor activity in the range IC50 1.1-47 mu M on a panel of four distinct human cancer cell lines.