Browsing by Author "Domínguez, J"

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    Pravastatin decreases cold ischemia -: But not alloantigen-dependent transplant arteriosclerosis
    (2003) Domínguez, J; Schultz, M
    Background. Alloantigen mismatch and cold ischemia have been shown to induce transplant arteriosclerosis. Pravastatin (PR) decreases arteriosclerosis probably related to an immunosuppressive effect. Statins posses other nonimmune properties that may be beneficial to transplantation. We studied the effect of PR on cold ischemia and alloatntigen-induced transplant arteriosclerosis in syngeneic (SYN) and allogeneic (ALLO) aortic transplantation models.