Browsing by Author "Diaz-Ferrer, Javier"

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    Genetic Risk Score Correlates with Immune Profile and Risk of HCC and Cirrhosis development in Hispanics with MASLD
    (2025) Fu, Siyu; Groothuismink, Anthonie; Balderramo, Domingo; Mattos, Angelo Z.; Hoppe, Lisia; Carrera, Enrique; Diaz-Ferrer, Javier; Prieto, Jhon; Banales, Jesus M.; Arrese Jímenez, Marco Antonio; Hansen, Bettina E.; Boonstra, Andre; Debes, José D.
    Genetic risk score and immune dysregulations have been separately associated with the development of hepatocellular carcinoma (HCC) and cirrhosis in the context of metabolic associated steatotic liver disease (MASLD). Latin America has the highest prevalence of MASLD worldwide. However, the relationship between genetic risk scores, immune dysregulation and MASLD has not been explored.
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    Liver transplantation in Latin America: reality and challenges
    (2023) Aguirre-Villarreal, David; Servin-Rojas, Maximiliano; Sanchez-Cedillo, Aczel; Chavez-Villa, Mariana; Hernandez-Alejandro, Roberto; Arab, Juan Pablo; Ruiz, Isaac; Avendano-Castro, Karla P.; Matamoros, Maria A.; Adames-Almengor, Enrique; Diaz-Ferrer, Javier; Rodriguez-Aguilar, Erika Faride; Paez-Zayas, Victor Manuel; Contreras, Alan G.; Alvares-da-Silva, Mario R.; Mendizabal, Manuel; Oliveira, Claudia P.; Navasa, Miquel; Garcia-Juarez, Ignacio
    Healthcare systems in Latin America are broadly heterogeneous, but all of them are burdened by a dramatic rise in liver disease. Some challenges that these countries face include an increase in patients requiring a transplant, insufficient rates of organ donation, delayed referral, and inequitable or suboptimal access to liver transplant pro-grams and post-transplant care. This could be improved by expanding the donor pool through the implementation of education programs for citizens and referring physicians, as well as the inclusion of extended criteria donors, living donors and split liver transplantation. Addressing these shortcomings will require national shifts aimed at improving infrastructure, increasing awareness of organ donation, training medical personnel, and providing equitable access to care for all patients.