Browsing by Author "DWORSKY, ME"

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    PREVALENCE AND IMPORTANCE OF CONGENITAL CYTOMEGALOVIRUS-INFECTION IN 3 DIFFERENT POPULATIONS
    (1982) STAGNO, S; DWORSKY, ME; TORRES, J; MESA, T; HIRSH, T
    A Chilean population was compared to low-income and middle/upper-class populations in Birmingham, Alabama [USA], with regard to prevalence of congenital cytomegalovirus infection as well as the importance of this infection in neonatal deaths. In the highly seroimmune Chilean (98%) and low-income Birmingham (82%) groups, congenital infections occurred more often (1.7% and 1.9%, respectively), than in the less immune (56%) middle/upper-income group in Birmingham (0.6%). In 407 autopsies reviewed in Chile no neonatal deaths were attributed to cytomegalic inclusion disease; in Birmingham cytomegalovirus was the cause of death in 9 of 938 (1%) newborn infants. Evidently, despite an apparent lack of protection against intrauterine transmission, maternal immunity reduces the risk of severe fetal infection.