Browsing by Author "Cortes Arancibia, Sandra Isabel"

Now showing 1 - 3 of 3
  • Thumbnail Image
    Item
    Air Pollution and Cardiorespiratory Changes in Older Adults Living in a Polluted Area in Central Chile
    (SAGE PUBLICATIONS LTD, 2022) Cortes Arancibia, Sandra Isabel; Leiva Cisternas, Cinthya Aracely; Ojeda Valenzuela, María José; Bustamante-Ara, Natalia; Wambaa, Wanjiku; Domínguez, Alan; Pasten Salvo, Carlos; Rodriguez Peralta, Camila; Rojas Arenas, Barbara; Vargas Mesa, Diego; Ahumada Padilla Ericka Del Pilar
    One recognized cause of cardiorespiratory diseases is air pollution. Older adults (OA) are one of the most vulnerable groups that suffer from its adverse effects. The objective of the study was to analyze the association between exposure to air pollution and changes in cardiorespiratory variables in OA. Observational prospective cohort study. Health questionnaires. blood pressure (BP) measurements, lung functions, respiratory symptoms, physical activity levels, and physical fitness in high and low exposure to air pollution were all methods used in evaluating OAs in communes with high contamination rates. Linear and logistic models were created to adjust for variables of interest. A total of 92 OA participated in this study. 73.9% of the subjects were women with 72.3 +/- 5.6 years. 46.7% were obese, while 12.1% consumed tobacco. The most prevalent diseases found were hypertension, diabetes, and cardiovascular disease. Adjusted linear models maintained an increase for systolic BP of 6.77 mmHg (95% CI: 1.04-12.51), and diastolic of 3.51 mmHg (95% CI: 0.72-6.29), during the period of high exposure to air pollution. The adjusted logistic regression model indicated that, during the period of high exposure to air pollution increase the respiratory symptoms 4 times more (OR: 4.43, 95% CI: 2.07-10.04) in the OA. The results are consistent with an adverse effect on cardiorespiratory variables in periods of high exposure to air pollution in the OA population.
  • Thumbnail Image
    Item
    Exposure to pesticides in Chile and its relationship with carcinogenic potential: a review
    (Frontiers Media SA, 2025) Munoz-Quezada, María Teresa; Iglesias, Verónica; Zúñiga-Venegas, Liliana; Pancetti, Floria; Foerster, Claudia; Landeros, Natalia; Lucero, Boris; Schwantes, Daniel; Cortes Arancibia, Sandra Isabel
    Background: The widespread application of pesticides in agriculture and the consequent heightened human exposure to these potentially harmful substances present considerable environmental and health risks. The potential link to cancer is particularly concerning, underscoring the urgent need for more sustainable and health-conscious agricultural practices. Pesticides are pervasive global contaminants, with exposure occurring through various routes. Improper use is associated with genotoxicity, neurobehavioral problems, thyroid dysfunction, reproductive issues, and cancer, among other deleterious damages. While pesticide exposure is evident in Chile, a direct link to cancer remains uncertain. Objective: To examine the scientific evidence on pesticides exposure in the environment and human populations, and its relationship with cancer in Chilean territory. Methods: The search for original articles was performed in international peer-reviewed scientific databases, including Scopus, Web of Science (WoS), and PubMed Advanced Search Builder. Following the PRISMA extension for review guidelines, the search included studies on environmental pesticide exposure, human biomarker assessments, experimental investigations, and the potential pesticide-cancer associations in Chile. Foreign studies, systematic reviews, and meta-analyses were excluded. Results: Among the 83 qualifying studies conducted between 1996 and 2024, elevated pesticide exposure risks were documented, with 71% indicating high concentrations that may pose health risk. Additionally, 20% of studies reported significant chlorinated compounds, including organochlorines (OCs) and polychlorinated biphenyls (PCBs), while 79.5% identified carcinogenic to humans classified by the International Agency for Research on Cancer. The review emphasizes the urgent need to update pesticide-related regulations in Chile, including implementing bans or restrictions on carcinogenic pesticides and establishing stricter standards for allowable pesticide residue levels in food. Conclusion: Long-term epidemiological studies are essential to establishing concrete links between pesticide exposure and specific types of cancer. Additionally, investigating epigenetic markers associated with pesticide exposure, especially in occupational settings, is critical. Furthermore, allocating resources and prioritizing further research is fundamental, particularly in regions with substantial agricultural exposure.
  • Thumbnail Image
    Item
    Geographic variability in the Chilean dietary carbon footprint: Major food contributors and associated factors
    (2023) Gutiérrez, Soledad; Cortes Arancibia, Sandra Isabel; Ruedlinger Standen, Jenny; Ojeda Valenzuela, Maria Jose; Fresán, Ujué; CEDEUS (Chile)
    Anthropogenic greenhouse gas emissions (GHGE) are behind climate change. In Chile, food system is the second source of GHGE. Changing Chileans dietary patterns is key to reducing such emissions. There is geographic variability in terms of dietary patterns within the country. Here we investigated the dietary GHGE in five different geographical zones, along with the main contributing food groups and socio-demographic variables. Data for 4676 individuals were obtained from the 2010–2011 National Survey of Food Consumption. The carbon footprint value of each food was obtained from studies using life cycle assessment methodology. Median and percentiles of dietary GHGE were calculated, expressed in kilograms of carbon dioxide equivalent per person per day (kgCO2eq/person/d) and compared among zones by Kruskal-Wallis and Dunn's tests. Logistic regression models were fitted to analyzed associations among the variables of interest and quartiles of GHGE. Diet-related GHGE ranged from 3.50 (2.34–5.12) in the North-Central Zone to 4.66 (2.89–6.69) kgCO2eq/person/d in the South zone. Meat accounted for 53–58% of the GHGE in all the zones, followed by dairy products with 12–13%. Higher GHGE were significantly associated with energy intake (kcal/d) in all of the zones, with high socioeconomic level in the North-Central, South and Metropolitan zones, and with urban residence in the South-Central zone. Tailored policies considering geographic variability are warranted to promote healthy and sustainable diets among the Chilean population.