Browsing by Author "Cortínez, Luis I."

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    Anesthesia for electroconvulsive therapy: clinical experience
    (Wiley, 2007) González, Aridane G.; Cortínez, Luis I.; Cuadra F., Juan Carlos de la; Carrasco, Elena; Rioseco, Alonso; Léniz, Pamela Wisnia
    OBJECTIVE: To assess the utility of propofol and succinylcholine in obtaining optimal convulsions and assuring patient safety during electroconvulsive therapy. PATIENTS AND METHODS: This was a prospective observational study of patients undergoing electroconvulsive therapy under general anesthesia with propofol and succinylcholine. We recorded patient characteristics, doses of propofol and succinylcholine, electroencephalographically-recorded duration of convulsions, and complications. Descriptive statistics were compiled and the data were subjected to analysis of correlations, comparison with the Student t test for independent samples, the Mann-Whitney U test, and analysis of variance. RESULTS: We studied 108 patients, 62% women and 38% men, 80% classified as ASA 1 and 20% as ASA 2. The patients underwent 844 sessions of electroconvulsive therapy; their mean (SD) age was 39.95 (18.09) years. The doses of propofol and succinylcholine were 1.34 (0.32) mgxkg(-1) and 1.35 (0.26) mgxkg(-1), respectively. The mean recorded duration of the first convulsion (29.87 [22.42] seconds) was negatively correlated with age (r = -0.12) and unrelated to propofol dose (r = 0.06) or body weight (r = 0.02). Male and schizophrenic patients had longer-lasting convulsions (P < .01). Cardiovascular complications occurred in 2.4% and psychomotor agitation in 1.4%; there were no respiratory complications, musculoskeletal injuries, nausea, or vomiting. CONCLUSIONS: Electroconvulsive therapy can be safely applied in an operating room or similar space undergeneral anesthesia and with a neuromuscular blockade in order to prevent psychological or musculoskeletal trauma. Propofol did not affect the convulsions at the dosages administered.
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    Anesthesia for electroconvulsive therapy: clinical experience
    (2007) González, Aridane G.; Cortínez, Luis I.; Cuadra F., Juan Carlos de la; Carrasco, Elena; Rioseco, Alonso; Léniz, Pamela Wisnia
    OBJECTIVE: To assess the utility of propofol and succinylcholine in obtaining optimal convulsions and assuring patient safety during electroconvulsive therapy. PATIENTS AND METHODS: This was a prospective observational study of patients undergoing electroconvulsive therapy under general anesthesia with propofol and succinylcholine. We recorded patient characteristics, doses of propofol and succinylcholine, electroencephalographically-recorded duration of convulsions, and complications. Descriptive statistics were compiled and the data were subjected to analysis of correlations, comparison with the Student t test for independent samples, the Mann-Whitney U test, and analysis of variance. RESULTS: We studied 108 patients, 62% women and 38% men, 80% classified as ASA 1 and 20% as ASA 2. The patients underwent 844 sessions of electroconvulsive therapy; their mean (SD) age was 39.95 (18.09) years. The doses of propofol and succinylcholine were 1.34 (0.32) mgxkg(-1) and 1.35 (0.26) mgxkg(-1), respectively. The mean recorded duration of the first convulsion (29.87 [22.42] seconds) was negatively correlated with age (r = -0.12) and unrelated to propofol dose (r = 0.06) or body weight (r = 0.02). Male and schizophrenic patients had longer-lasting convulsions (P < .01). Cardiovascular complications occurred in 2.4% and psychomotor agitation in 1.4%; there were no respiratory complications, musculoskeletal injuries, nausea, or vomiting. CONCLUSIONS: Electroconvulsive therapy can be safely applied in an operating room or similar space undergeneral anesthesia and with a neuromuscular blockade in order to prevent psychological or musculoskeletal trauma. Propofol did not affect the convulsions at the dosages administered.
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    Intraoperative electroencephalographic marker of preoperative frailty: a prospective cohort study
    (2023) Boncompte, Gonzalo; Sun, Haoqi; Elgueta Le-Beuffe, María Francisca; Benavides, Javiera; Carrasco, Marcela; Morales, María I.; Calderón, Natalia; Contreras, Victor; Westover, M. Brandon; Cortínez, Luis I.; Akeju, Oluwaseun; Pedemonte Trewhela, Juan Cristóbal
    Frailty was common in elderly patients undergoing non cardiac surgery. Electroencephalogram alpha-band power does not predict preoperative frailty above patients' age. Frailty predictions by machine learning algorithms, were not improved by the addition of electroencephalogram features. Frailty might be different to the concept of brain vulnerability, accounting for a possible brain-body dissociation.