Browsing by Author "Corpechot, Christophe"

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    Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis
    (2024) Kowdley, Kris V.; Bowlus, Christopher L.; Levy, Cynthia; Akarca, Ulus S.; Alvares-da-Silva, Mario Reis; Andreone, Pietro; Arrese, Marco; Corpechot, Christophe; Francque, Sven M.; Heneghan, Michael A.; Invernizzi, Pietro; Jones, David; Kruger, Frederik C.; Lawitz, Eric; Mayo, Marlyn J.; Shiffman, Mitchell L.; Swain, Mark G.; Valera, Jose Miguel; Vargas, Victor; Vierling, John M.; Villamil, Alejandra; Addy, Carol; Dietrich, Julie; Germain, Jean-Michel; Mazain, Sarah; Rafailovic, Dragutin; Tadde, Bachirou; Miller, Benjamin; Shu, Jianfen; Zein, Claudia O.; Schattenberg, Jorn M.
    Background Primary biliary cholangitis is a rare, chronic cholestatic liver disease characterized by the destruction of interlobular bile ducts, leading to cholestasis and liver fibrosis. Whether elafibranor, an oral, dual peroxisome proliferator-activated receptor (PPAR) alpha and delta agonist, may have benefit as a treatment for primary biliary cholangitis is unknown.