Browsing by Author "Conget, Paulette"
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- ItemDexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells(2015) Contador, David; Ezquer, Fernando; Espinosa, Maximiliano; Arango Rodriguez, Martha; Puebla, Carlos; Sobrevía Luarte, Luis Alberto; Conget, Paulette
- ItemReplenishment of type VII collagen and re-epithelialization of chronically ulcerated skin after intradermal administration of allogeneic mesenchymal stromal cells in two patients with recessive dystrophic epidermolysis bullosa(INFORMA HEALTHCARE, 2010) Conget, Paulette; Rodriguez, Fernando; Kramer, Susanne; Allers, Carolina; Simon, Valeska; Palisson, Francis; Gonzalez, Sergio; Yubero, Maria J.In animal models it has been shown that mesenchymal stromal cells (MSC) contribute to skin regeneration and accelerate wound healing. We evaluated whether allogeneic MSC administration resulted in an improvement in the skin of two patients with recessive dystrophic epidermolysis bullosa (RDEB; OMIM 226600). Patients had absent type VII collagen immunohistofluorescence and since birth had suffered severe blistering and wounds that heal with scarring. Vehicle or 0.5x10