Browsing by Author "Chahuan Abde, Javier Nicolas"

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    Comparison of OLGA and OLGIM as predictors of gastric cancer in a Latin American population: the ECHOS Study
    (2024) Latorre Selvat, Gonzalo Ignacio; Silva Peña, Felipe Andres; Montero Jaras, Isabella; Bustamante Cartagena, Miguel Alonso; Dukes Berry, Eitan Ariel; Uribe Monasterio, Javier Andres; Corsi Sotelo, Oscar Felipe; Reyes Placencia, Diego Armando; Fuentes López, Eduardo; Pizarro Rojas, Margarita Alicia; Medel Jara, Patricio Andres; Torres, Javiera; Roa, Juan Carlos; Pizarro, Sebastian; Achurra Tirado, Pablo Andres; Donoso, Andres; Wichmann Pérez, Ignacio Alberto; Corvalan, Alejandro H.; Chahuan Abde, Javier Nicolas; Candia Balboa, Roberto Andres; Aguero, Carlos; Gonzalez, Robinson; Vargas, Jose Ignacio; Espino, Alberto; Camargo, M. Constanza; Shah, Shailja C.; Riquelme, Arnoldo
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    Letter: Potential impact of Helicobacter pylori infection on oesophageal disorders in chronic liver disease—Authors' reply
    (2024) Idalsoaga Ferrer, Francisco Javier; Diaz Piga, Luis Antonio; Ayares Campos, Gustavo Ignacio; Cabrera, Daniel; Chahuan Abde, Javier Nicolas; Monrroy Bravo, Hugo Alfonso; Halawi, Houssam; Arrese Jiménez, Marco Antonio; Arab Verdugo, Juan Pablo
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    Métodos diagnósticos para la detección de infección por Helicobacter pylori. ¿Cuál y cuándo deben solicitarse?
    (2022) Chahuan Abde, Javier Nicolas; Pizarro Rojas, Margarita Alicia; Riquelme Pérez, Arnoldo
    La infección gástrica por Helicobacter pylori tiene una pre-valencia variable a nivel mundial. En Latinoamérica, puede superar el 50% de infectados. Se asocia a patologías como la úlcera péptica, el cáncer gástrico, el linfoma MALT y la púrpura trombocitopénica inmune, entre otras. No hay un método diagnóstico óptimo y la presencia puede ser detectada tanto por métodos invasivos, que requieren una endoscopía digestiva alta, como no invasivos. Dentro de los invasivos, contamos con la prueba rápida de ureasa, la histología, las pruebas moleculares, como reacción en cadena de la poli-merasa, y el cultivo. Por su parte, los no invasivos incluyen la prueba de aire espirado, el antígeno en deposiciones de Helicobacter pylori, reacción en cadena de la polimerasa en deposiciones y la serología. La prueba diagnóstica a utilizar depende del escenario clínico, y deben conocerse los beneficios y debilidades de cada método. Es importante considerar la edad del paciente, sus factores de riesgo de cáncer gástrico, la necesidad de endoscopía por esta u otra causa, la disponibili-dad de las pruebas diagnósticas y el costo, entre otros.
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    Neurogastroenterology and motility disorders in patients with cirrhosis
    (Lippincott Williams and Wilkins, 2025) Idalsoaga Ferrer, Francisco Javier; Ayares Campos, Gustavo Ignacio; Blaney, Hanna; Cabrera, Daniel; Chahuan Abde, Javier Nicolas; Monrroy Bravo, Hugo Alfonso; Matar, Ayah; Halawi, Houssam; Arrese Jimenez Marco Antonio; Arab Verdugo, Juan Pablo; Díaz Piga, Luis Antonio
    Neurogastroenterology and motility disorders are complex gastrointestinal conditions that are prevalent worldwide, particularly affecting women and younger individuals. These conditions significantly impact the quality of life of people suffering from them. There is increasing evidence linking these disorders to cirrhosis, with a higher prevalence compared to the general population. However, the link between neurogastroenterology and motility disorders and cirrhosis remains unclear due to undefined mechanisms. In addition, managing these conditions in cirrhosis is often limited by the adverse effects of drugs commonly used for these disorders, presenting a significant clinical challenge in the routine management of patients with cirrhosis. This review delves into this connection, exploring potential pathophysiological links and clinical interventions between neurogastroenterology disorders and cirrhosis.
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    Review article: Oesophageal disorders in chronic liver disease
    (WILEY, 2024) Idalsoaga Ferrer, Francisco Javier; Diaz Piga, Luis Antonio; Ayares Campos, Gustavo Ignacio; Cabrera, Daniel; Chahuan Abde, Javier Nicolas; Monrroy Bravo, Hugo Alfonso; Halawi, Houssam; Arrese Jimenez, Marco Antonio; Arab Verdugo, Juan Pablo
    Background: Oesophageal disorders and chronic liver disease are common worldwide and significantly impact quality of life. The intricate link between these conditions, including how oesophageal disorders like GERD, Barrett's oesophagus and oesophageal cancer affect and are affected by chronic liver disease, remains poorly understood. Aims: To review the relationship between oesophageal disorders and chronic liver disease, evaluating epidemiology, pathophysiology and therapeutic factors. Methods: We reviewed the literature on the relationship between oesophageal disorders and chronic liver disease, including cirrhosis, using the PubMed database Results: Oesophageal disorders such as gastroesophageal reflux disease, Barrett's oesophagus, oesophageal cancer, oesophageal motor disorders and oesophageal candidiasis are prevalent among individuals with cirrhosis, exacerbating the burden of liver disease. These diseases have a multifaceted symptomatology and pathogenic basis, posing a significant challenge in cirrhotic patients that necessitates careful diagnosis and management. Additionally, therapies frequently used for these diseases, such as proton pump inhibitors, require careful consideration in cirrhotic patients due to potential adverse effects and altered pharmacokinetics. Managing oesophageal disorders in cirrhotic patients requires a cautious approach due to possible interactions with medications and the risk of adverse effects. Furthermore, symptoms associated with these conditions are often exacerbated by common interventions in patients with cirrhosis, such as band ligation for oesophageal varices. Conclusions: Oesophageal disorders are common in cirrhosis and increase the disease burden. These conditions require careful management due to complex symptoms and treatment risks. Proton pump inhibitors and other therapies must be used cautiously, as cirrhosis interventions can worsen symptoms.
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    Vascular malformation simulating a gastric subepithelial lesion: the risks of the bite-on-bite biopsy technique
    (2023) Candia Balboa, Roberto Andres; Arenas, Alex; Chahuan Abde, Javier Nicolas; Riquelme Pizarro, Carlos Rodrigo; Mendez Olivieri, Gonzalo Patricio