Browsing by Author "Cerda J."

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    Consolidado de recomendaciones del comité asesor de vacunas y estrategias de inmunización-cavei, sobre priorización de vacunación covid-19Consolidated recommendations of the Advisory Committee on Vaccines and Immunization Strategies- on prioritizing COVID-19 vaccination
    (2021) Dabanch J.; Bastías M.; Endeiza M.L.; Díaz E.; Inostroza J.; Cerda J.; Santillana S.; Rodríguez J.; González C.; Rodríguez M.; Pizarro A.; Dabanch J.; Bastías M.; González C.; Endeiza M.L.; Díaz E.; Inostroza J.; Cerda J.; Santillana S.; Rodríguez J.; Rodríguez M.; Pizarro A.; Dabanch J.
    © 2021, Sociedad Chilena de Infectologia. All rights reserved.COVID-19 is a global public health issue due to its epidemic nature that, to date, lacks pharmacological treatment. However, some COVID-19 vaccines have been authorized for emergency use, although the duration of their protection, their ability to interrupt viral transmission, and their efficacy against emerging variants of SARS-CoV-2 are being studied. Chile's SARS-CoV-2 vaccination campaign required design and planning, like any other campaign. This process included the prioritization of risk groups for vaccination given the limited supply of COVID-19 vaccines globally. Throughout 2020, CAVEI issued recommendations on the prioritization of population groups to be vaccinated against SARS-CoV-2 in response to different needs and in accordance with available evidence. These recommendations are consolidated in Table 1 in this report. In summary, it was recommended that healthcare workers, people in long-term residences and essential State personnel be vaccinated in phase 1. In phase 2, persons over 65 years of age and people with comorbidities. In phase 3, essential tasks workers and, lastly, the general population.
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    Profile of adult patients hospitalized with COVID-19 before and after introduction of SARS-CoV-2 vaccinesPerfil de pacientes adultos hospitalizados por COVID-19 antes y después de la introducción de las vacunas contra SARS-CoV-2
    (Springer, 2023) Potin M.; Aljaro S.; Lopez S.; Uauy O.; Cifuentes C.; Cerda J.; Valenzuela D.; CEDEUS (Chile)
    © 2023, Sociedad Chilena de Infectologia. All rights reserved.Background: During the COVID-19 pandemic, the early prioriti-zation of SARS-CoV-2 vaccines for older adults may have affected the characteristics of hospitalized COVID-19 patients over time. Aim: To compare the clinical characteristics and outcomes of adult patients admitted for COVID-19 before (PER1) and after (PER2) the initiation of mass vaccination for SARS-CoV-2. Methods: Data on age, gender, comorbidities, complications, and outcomes of adult patients hospitalized for COVID-19 in a private clinic of Santiago, Chile, were collected. Scores for COVID-19 severity and nutritional risk were calculated. Results: In PER2, patients were younger but had similar comorbidities, except for a higher prevalence of overweight and obesity compared to PER1. Unvaccinated COVID-19 patients in PER2 required more invasive ventilatory support (38.9% vs. 14.3%, p = 0.03) and had a higher severity score (six) than vaccinated patients (five, p = 0.048). The variables that best predicted mortality were age ≥ 60 years (OR 28,995) and the presence of nutritional risk (OR 5,246). Discussion: Changes in the profile and outcomes of hospitalized patients during the COVID-19 pandemic are associated with the prioritization of SARS-CoV-2 vaccines and their protective effect in reducing hospitalizations and disease severity in older adults.