Browsing by Author "Carlos Flores, Juan"

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    Catheter-associated bloodstream infection caused by Leifsonia aquatica in a haemodialysis patient: a case report
    (SOC GENERAL MICROBIOLOGY, 2012) Porte, Lorena; Soto, Andres; Andrighetti, Daniela; Dabanch, Jeannette; Braun, Stephanie; Saldivia, Alejandra; Carlos Flores, Juan; Wozniak, Aniela; Garcia, Patricia; Weitzel, Thomas
    Leifsonia aquatica is an aquatic coryneform rod that is capable of forming biofilms in environmental water sources. It has rarely been associated with human infections and its pathogenicity and clinical significance are uncertain. We describe a case of catheter-related bloodstream infection in a haemodialysis patient. The isolate grew on conventional media as a yellow-pigmented colony, but identification required molecular methods. Although the strain displayed reduced sensitivity to vancomycin, the clinical outcome was favourable after catheter removal and intravenous treatment with this antibiotic. Our report gives further evidence of the capability of this aquatic bacterium to cause human infection.
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    Niños y adolescentes con necesidades especiales de atención en salud: prevalencia hospitalaria y riesgos asociados
    (SOC MEDICA SANTIAGO, 2012) Carlos Flores, Juan; Carrillo, Daniela; Karzulovic, Lorena; Cerda, Jaime; Araya, Gabriela; Soledad Matus, Maria; Llevenes, Guillermo; Menchaca, Gonzalo; Vargas, Nelson A.
    Background: "Children with special health care needs" (CSHCN) is a novel definition for pediatric patients with chronic diseases, adopted by the Chilean Pediatric Society in 2008. As life expectancy in Chile increases, prevalence of CSHCN is progressively growing, leading to higher health costs. Aim: To describe the epidemiological profile and clinical characteristics of hospitalized CSHCN, and compare the risk assessment of adverse events during hospitalization using two definitions for CSHCN. Patients and Methods: A cohort of hospitalized CSHCN in a Pediatric Center at Santiago, Chile, was followed from September to December 2009. Clinical and demographic data were registered in a database, including admission to intensive care unit (ICU), nosocomial infections and prolonged hospitalization (> 7 days). Incidence ratios for these events were compared between CSHCN and non-CSHCN, and between children attended by three or more health care professionals (CSHCN-3) and non-CSHCN. Results: Nine hundred twenty patients were included (54% male), with a median age 14 months (0-221) and median days of hospitalization 4 days (1-229). Prevalence of CSHCN was 60.8% of hospitalized children. When using CSHCN definition and comparing with non-CSHCN, no excess of risk was documented. On the other hand, prevalence of CSHCN-3 was 19.9%. Compared to non-CSHCN, these patients had a higher risk of ICU admission (relative risk (RR) 1.58; 95% confidence intervals (CI) = 1.22-2.05; p < 0.01), nosocomial infections (RR 2.28; 95% CI = 1.54-3.39; p < 0.001) and prolonged hospitalization (RR 1.99; 95% CI = 1.52-2.60; p < 0.001). Conclusions: One in five hospitalized children met CSHCN-3 definition. These patients had an increased risk of adverse events during their hospitalization compared to non-CSHCN. (Rev Med Chile 2012; 140: 458-465).