Browsing by Author "Cardona, AFR"

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    Kinetics of the formation and hydrolysis of the Schiff bases of pyridoxal 5'-phosphate and copolypeptides containing L-lysine and aromatic L-amino acids
    (1996) delVado, MAG; Perez, MPM; Cardona, AFR; Echevarria, GR; Blanco, JGS; Blanco, FG
    We determined the apparent rate constants of formation (k(1)) and hydrolysis (k(2)) of the Schiff bases formed between pyridoxal 5'-phosphate and copolymers of L-lysine-L-tyrosine and L-lysine-L-phenylalanine, at different pH values, at temperature of 25 degrees C and an ionic strength of 0.1 M. The values of the rate constant of formation obtained for the systems of the present work are greater than these for the PLP-poly-L-lysine system in all the range of pH studied, due to the presence of aromatic groups in the lateral chains of the polypeptide. The existence of these groups favors the presence of a few polar environment for the Schiff bases.