Browsing by Author "Caironi, Pietro"

Now showing 1 - 3 of 3
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    Anatomical and functional intrapulmonary shunt in acute respiratory distress syndrome
    (LIPPINCOTT WILLIAMS & WILKINS, 2008) Cressoni, Massimo; Caironi, Pietro; Polli, Federico; Carlesso, Eleonora; Chiumello, Davide; Cadringher, Paolo; Quintel, Micheal; Ranieri, Vito Marco; Bugedo, Guillermo; Gattinoni, Luciano
    Objectives. The lung-protective strategy employs positive end expiratory pressure to keep open otherwise collapsed lung regions (anatomical recruitment). Improvement in venous admixture with positive end-expiratory pressure indicates functional recruitment to better gas exchange, which is not necessarily related to anatomical recruitment, because of possible global/regional perfusion modifications. Therefore, we aimed to assess the value of venous admixture (functional shunt) in estimating the fraction of nonaerated lung tissue (anatomical shunt compartment) and to describe their relationship.
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    Lung Opening and Closing during Ventilation of Acute Respiratory Distress Syndrome
    (AMER THORACIC SOC, 2010) Caironi, Pietro; Cressoni, Massimo; Chiumello, Davide; Ranieri, Marco; Quintel, Michael; Russo, Sebastiano G.; Cornejo, Rodrigo; Bugedo, Guillermo; Carlesso, Eleonora; Russo, Riccarda; Caspani, Luisa; Gattinoni, Luciano
    Rationale The effects of high positive end-expiratory pressure (PEEP) strictly depend on lung recruitability, which varies widely during acute respiratory distress syndrome (ARDS). Unfortunately, increasing PEEP may lead to opposing effects on two main factors potentially worsening the lung injury, that is, alveolar strain and intratidal opening and closing, being detrimental (increasing the former) or beneficial (decreasing the latter).
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    Lung Recruitability Is Better Estimated According to the Berlin Definition of Acute Respiratory Distress Syndrome at Standard 5 cm H2O Rather Than Higher Positive End-Expiratory Pressure : a Retrospective Cohort Study
    (2015) Caironi, Pietro; Carlesso, Eleonora; Cressoni, Massimo; Chiumello, Davide; Moerer, Onner; Chiurazzi, Chiara; Brioni, Matteo; Bottino, Nicola; Lazzerini, Marco; Bugedo Tarraza, Guillermo; Quintel, Michael; Ranieri, V. Marco; Gattinoni, Luciano