Browsing by Author "Bustos O., Gonzalo"
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- ItemFunctional and biochemical characteristics of a putative quisqualate-type receptor in rat striatum: Effect of brain lesions(1986) Rudolph, Maria Isolde; Bustos O., GonzaloExcitatory amino acids such asl-glutamate (Glu) and quisqualate (QUIS) markedly potentiated K+-evoked release of exogeneous [3H]dopamine (DA) from rat striatal slices. Intranstriatal kainic acid injections resulted in a total disappearance of the stimulatory effects of Glu on evoked-release of [3H]DA as well as in a parallel reduction in the maximal number (Bmax) of ad-aspartate-insensitivel-[3H]Glu binding site in striatal particulate fractions. Following cortical ablation, the potentiating effect of Glu on [3H]DA release in decorticated striatal slices lasted longer, compared to normal slices, and occured during the 2nd min following K+-depolarization. However, the extent (%) of Glu stimulation on [3H]DA release remained the same in decorticated and normal striatal slices. Cortical ablation produced also a significant decrease in the Bmax and in theK d' of thed-aspartateinsensitive binding site towardsl[3H]Glu. These results support the proposal that thed-aspartate-insensitive Glu binding site is somehow related to an amino acid receptor-mediated modulation of dopaminergic transmission in the rat corpus striatum.
- ItemNMDA Receptors Mediate an Early Up-regulation of Brain-derived Neurotrophic Factor Expression in Substantia Nigra in a Rat Model of Presymptomatic Parkinson's Disease(2009) Bustos O., Gonzalo; Abarca Urbina, Jorge Daniel; Campusano Astorga, Jorge Mauricio
- ItemNon-canonical function of IRE1 alpha determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics(2019) Carreras-Sureda, A.; Jana, F.; Urra, H.; Durand, S.; Mortenson, D.E.; Sagredo, A.; Bustos O., Gonzalo; Hazari, Y.; Ramos-Fernandez, E.; Inestrosa Cantín, Nibaldo; Sassano, M.L.; Pihan, P.; Van Vliet, A.R.; Gonzalez-Quiroz, M.; Torres, A.K.; Tapia-Rojas, Cheril; Kerkhofs, M.; Vicente, R.; Kaufman, R.J.; Gonzalez-Billault, C.; Wiseman, R.L.; Agostinis, P.; Bultynck, G.; Court G., Felipe; Kroemer, G.; Cardenas, J.C.; Hetz, C.
- ItemRegulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum : in vivo microdialysis studies(1992) Bustos O., Gonzalo; Abarca, Jorge; Forray Claps, María Inés; Gysling Caselli, Katia; Bradberry, Charles W.; Roth, Robert H.