Browsing by Author "Briones-Labarca, Vilbett"

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    Effect of Extraction Methods and In Vitro Bio-Accessibility of Microencapsulated Lemon Extract
    (2022) Giovagnoli-Vicuna, Claudia; Briones-Labarca, Vilbett; Soledad Romero, Maria; Giordano, Ady; Pizarro, Sebastian
    The extraction of bioactive compounds from fruits, such as lemon, has gained relevance because these compounds have beneficial properties for health, such as antioxidant and anticancer properties; however, the extraction method can significantly affect these properties. High hydrostatic pressure and ultrasound, as emerging extraction methods, constitute an alternative to conventional extraction, improving extractability and obtaining extracts rich in bioactive compounds. Therefore, lemon extracts (LEs) were obtained by conventional (orbital shaking), ultrasound-assisted, and high-hydrostatic-pressure extraction. Extracts were then microencapsulated with maltodextrin at 10% (M10), 20% (M20), and 30% (M30). The impact of microencapsulation on LEs physicochemical properties, phenolics (TPC), flavonoids (TFC) and relative bio-accessibility (RB) was evaluated. M30 promoted a higher microencapsulation efficiency for TPC and TFC, and a longer time required for microcapsules to dissolve in water, as moisture content, water activity and hygroscopicity decreased. The RBs of TPC and TFC were higher in microcapsules with M30, and lower when conventional extraction was used. The data suggest that microencapsulated LE is promising as it protects the bioactivity of phenolic compounds. In addition, this freeze-dried product can be utilized as a functional ingredient for food or supplement formulations.
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    Encapsulation of papaya seed oil in casein-alginate-based shell materials
    (2024) Canas-Sarazia, Rail; Briones-Labarca, Vilbett; Giovagnoli-Vicuna, Claudia
    This study aimed to develop papaya seed oil macrocapsules using ionotropic gelation encapsulation with casein and sodium alginate as shell materials. Mechanical stability and physical properties, assessed via response surface methodology, were used to determine optimal conditions. Bioaccessibility and oil release post in -vitro gastrointestinal digestion were also quantified. Independent variables (papaya seed oil concentration, calcium chloride percentage, and pH) were examined, revealing correlation coefficients (R2) of 0.938, 0.957, 0.954, and 0.845 for elastic limit, Young modulus, oil loss capacity, and capsule diameter, respectively. Optimal encapsulation conditions were identified as 60 % papaya seed oil, 0.5 % calcium chloride (w/v), and pH 2, resulting in macrocapsules with an elastic limit of 176.84 Pa, Young modulus of 4.44 Pa, oil loss capacity of 19.81 %, and a capsule diameter of 2.727 mm. In -vitro studies indicated a target oil release of 52.23 %, primarily in the intestinal phase, with a bioaccessibility of 75.36 %. This study underscores the impact of encapsulation process conditions on macrocapsule properties and highlights the potential application of casein alginate macrocapsules as oral delivery vehicles for lipophilic compounds in the food and nutraceuticals industry.