Browsing by Author "Baudrand Biggs, René"

Now showing 1 - 20 of 48
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    A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics
    (2015) Baudrand Biggs, René; Goodarzi, Mark O.; Vaidya, Anand; Underwood, Patricia C.; Williams, Jonathan S.; Jeunemaitre, Xavier; Hopkins, Paul N.; Brown, Nancy; Raby, Benjamin A.; Lasky-Su, Jessica; Adler, Gail K.; Cui, Jinrui; Guo, Xiuqing; Taylor, Kent D.; Chen, Yii-Der I.; Xiang, Anny; Raffel, Leslie J.; Buchanan, Thomas A.; Rotter, Jerome I.; Williams, Gordon H.; Pojoga, Luminita H.
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    Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature.
    (2008) Acevedo Claros, Francisco Nicolás; Baudrand Biggs, René; Letelier Saavedra, Luz María; Pablo Gaete
    Actinomycosis is a rare, chronic disease caused by a group of anaerobic Gram-positive bacteria that normally colonize the mouth, colon, and urogenital tract. Infection involving the cervicofacial area is the most common clinical presentation, followed by pelvic region and thoracic involvement. Due to its propensity to mimic many other diseases and its wide variety of symptoms, clinicians should be aware of its multiple presentations and its ability to be a 'great pretender'. We describe herein three cases of unusual presentation: an inferior caval vein syndrome, an acute cholecystitis, and an acute cardiac tamponade. We review the literature on its epidemiology, clinical presentation, diagnosis, treatment, and prognosis.
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    Age-Related Changes in 11 beta-Hydroxysteroid Dehydrogenase Type 2 Activity in Normotensive Subjects
    (2013) Campino Johnson, María del Carmen; Martínez Aguayo, Alejandro Gregorio; Baudrand Biggs, René; Carvajal Maldonado, Cristián Andrés; Aglony Imbarack, Marlene Elizabeth; García Bruce, Hernán; Padilla Pérez, Oslando; Kalergis Parra, Alexis Mikes; Fardella B., Carlos
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    Aldosterona e IL-17 en la génesis de la hipertensión arterial mineralocorticoídea, un estudio ex vivo
    (2016) Vecchiola Cárdenas, Andrea Paola; Cristóbal Fuentes, Z.; Muñoz Durango, Natalia; Tapia Castillo, Alejandra; González Gómez, Luis M.; Baudrand Biggs, René; Carvajal Maldonado, Cristián Andrés; Campino Johnson, María del Carmen; Kalergis Parra, Alexis Mikes; Carlos, F.; Lagos, A.; Fardella B., Carlos; Vecchiola Cárdenas, Andrea Paola; Cristóbal Fuentes, Z.; Muñoz Durango, Natalia; Tapia Castillo, Alejandra; González Gómez, Luis M.; Baudrand Biggs, René; Carvajal Maldonado, Cristián Andrés; Campino Johnson, María del Carmen; Kalergis Parra, Alexis Mikes; Carlos, F.; Lagos, A.; Fardella B., Carlos
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    Aldosterone Production and Signaling Dysregulation in Obesity
    (2016) Vecchiola Cárdenas, Andrea Paola; Lagos, C.; Carvajal Maldonado, Cristián Andrés; Baudrand Biggs, René; Fardella B., Carlos
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    Aldosterone's mechanism of action : roles of lysine-specific demethylase 1 caveolin and striatin
    (2014) Baudrand Biggs, René; Pojoga, L.; Romero, J.; Williams, G
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    Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis
    (2015) Pizarro, M.; Solís, Nancy; Quintero, P.; Barrera Martínez, Francisco; Cabrera, D.; Rojas-de Santiago, P.; Arab Verdugo, Juan Pablo; Padilla, O.; Roa Strauch, Juan Carlos Enrique; Moshage, H.; Wree, A.; Inzaugarat, E.; Feldstein, A.; Fardella B., Carlos; Baudrand Biggs, René; Riquelme, A.; Arrese Jiménez, Marco
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    Bursitis tuberculosa: caso clinico
    (Sociedad Médica de Santiago, 2002) Pérez, Carlos; Rojas González, Álvaro Miguel; Baudrand Biggs, René; González Bombardiere, Sergio; Fontboté Riesco, Cristián Antonio
    We report a previously healthy 51 years old woman with a one year history of pain in the left hip associated with a mass without fever or local inflammatory changes. Magnetic resonance imaging located the mass in the medial gluteal muscle. The pathological examination of the mass disclosed unspecific inflammatory changes. Due to worsening of pain, a left throchanteric bursitis was diagnosed two weeks later and a throchanteric bursectomy was performed, obtaining a second biopsy. Aerobic, anaerobic and fungal cultures were negative. Lowenstein-Jensen culture showed development of mycobacteria and a genetic probe confirmed the presence of Mycobacterium tuberculosis. The second biopsy also identified several granulomas with areas of caseation and the Ziehl-Nielsen stain was positive for acid fast bacilli. Osteoarticular tuberculosis, specially bursitis, shoulds be suspected in the presence of chronic pain associated with swelling.
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    Caveolin 1 modulates aldosterone-mediated pathways of glucose and lipid homeostasis
    (2016) Baudrand Biggs, René; Gupta, N.; Garza A.; Vaidya, A.; Leopold, J.; Hopkins, P.; Jeunemaitre, X.; Ferri, C.; Romero, J.; Williams, J.; Loscalzo, J.; Adler, G.; Williams, G.; Pojoga, L.
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    Clinical Update on Congenital Adrenal Hyperplasia: Recommendations from a Multidisciplinary Adrenal Program
    (2023) Uslar Nawrath, Thomas Hermann; Olmos Borzone, Roberto Ignacio; Martinez Aguayo, Alejandro; Baudrand Biggs, René
    Congenital adrenal hyperplasia (CAH) is a common genetic disorder in endocrinology, especially its milder clinical presentation, often caused by a partial or total deficiency of the 21-hydroxylase enzyme located in the adrenal cortex. CAH is characterized by the overproduction of androgen, along with variable degrees of cortisol and aldosterone deficiency. The age at diagnosis can provide some information about underlying mutations, with those diagnosed at birth/early infancy more likely to have severe enzymatic defects, which may include adrenal insufficiency, sexual development disorders, short stature in adulthood, hirsutism, and a higher risk for metabolic syndrome and infertility. Non-classic CAH, a milder form of CAH, is usually manifested later in life and is a common differential diagnosis of Polycystic Ovary Syndrome and should be actively evaluated during initial studies of clinical or biochemical hyperandrogenism. The main goals of CAH treatment are hormone supplementation for severe cases, controlling adrenal androgen overproduction to minimize long-term side effects, managing fertility and genetic counseling, and optimizing patients' quality of life.
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    Clinical, Biochemical, and Genetic Characteristics of "Nonclassic" Apparent Mineralocorticoid Excess Syndrome
    (2019) Tapia Castillo, Alejandra; Baudrand Biggs, René; Vaidya, Anand; Campino Johnson, María del Carmen; Allende, Fidel; Carvajal Maldonado, Cristián Andrés; Vecchiola Cárdenas, Andrea Paola; Lagos Arévalo, Carlos Fernando; Fuentes Zúñiga, Cristóbal Andrés; Fardella B., Carlos; Solari, Sandra; Martínez Aguayo, Alejandro Gregorio; García Bruce, Hernán; Valdivia, Carolina; Tapia Castillo, Alejandra; Baudrand Biggs, René; Vaidya, Anand; Campino Johnson, María del Carmen; Allende, Fidel; Carvajal Maldonado, Cristián Andrés; Vecchiola Cárdenas, Andrea Paola; Lagos Arévalo, Carlos Fernando; Fuentes Zúñiga, Cristóbal Andrés; Fardella B., Carlos; Solari, Sandra; Martínez Aguayo, Alejandro Gregorio; García Bruce, Hernán; Valdivia, Carolina
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    Computed Tomography and Adrenal Venous Sampling in the Diagnosis of Unilateral Primary Aldosteronism
    (2018) Williams, Tracy A.; Burrello, Jacopo; Sechi, Leonardo A.; Fardella B., Carlos; Matrozova, Joanna; Adolf, Christian; Baudrand Biggs, René; Bernardi, Stella; Beuschlein, Felix; Catena, Cristiana; Doumas, Michalis; Fallo, Francesco; Giacchetti, Gilbert
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    Continuum of Renin-Independent Aldosteronism in Normotension
    (2017) Baudrand Biggs, René; Guarda Vega, Francisco; Fardella B., Carlos; Hundemer, G.; Brown, J.; Williams, G.; Vaidya, A.
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    Cortisol dysregulation in obesity-related metabolic disorders
    (2015) Baudrand Biggs, René; Vaidya, A.
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    Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension
    (2016) Martínez Aguayo, Alejandro Gregorio; Campino Johnson, María del Carmen; Baudrand Biggs, René; Carvajal, C.; García Bruce, Hernán; Aglony Imbarack, Marlene Elizabeth; Bancalar, R.; García, L.; Loureiro Pérez, Carolina Andrea; Vecchiola Cárdenas, Andrea Paola; Tapia Castillo, A.; Valdivia, C.; Sanhueza, S.; Fuentes, C.; Lagos, C.; Solari, S.; Allende, Fidel; Kalergis Parra, Alexis Mikes; Fardella B., Carlos; Martínez Aguayo, Alejandro Gregorio; Campino Johnson, María del Carmen; Baudrand Biggs, René; Carvajal, C.; García Bruce, Hernán; Aglony Imbarack, Marlene Elizabeth; Bancalar, R.; García, L.; Loureiro Pérez, Carolina Andrea; Vecchiola Cárdenas, Andrea Paola; Tapia Castillo, A.; Valdivia, C.; Sanhueza, S.; Fuentes, C.; Lagos, C.; Solari, S.; Allende, Fidel; Kalergis Parra, Alexis Mikes; Fardella B., Carlos
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    Depressive symptoms are associated with higher morning plasma cortisol in primary care subjects
    (2018) Capponi, Valentina; Carrasco, Carmen; Macchiavello, Stefano; Undurraga, Juan; Campino Johnson, María del Carmen; Carvajal, Cristian; Gomez, Teresita; Weiss, Cristian; Aedo Campos, Igor Iván; Vecchiola Cárdenas, Andrea Paola; Allende, Fidel; Solari, Sandra; Fardella B., Carlos; Baudrand Biggs, René; Capponi, Valentina; Carrasco, Carmen; Macchiavello, Stefano; Undurraga, Juan; Campino Johnson, María del Carmen; Carvajal, Cristian; Gomez, Teresita; Weiss, Cristian; Aedo Campos, Igor Iván; Vecchiola, Andrea; Allende, Fidel; Solari, Sandra; Fardella B., Carlos; Baudrand Biggs, René
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    Detection of a novel severe mutation affecting the CYP21A2 gene in a Chilean male with salt wasting congenital adrenal hyperplasia
    (2020) Arteaga U., Eugenio; Valenzuela Pino, Felipe Patricio; Lagos, C. F.; Lagos, M.; Martínez García, Alejandra Constanza; Baudrand Biggs, René; Carvajal Maldonado, Cristián Andrés; Fardella B., Carlos
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    Dietary Sodium Restriction Increases the Risk of Misinterpreting Mild Cases of Primary Aldosteronism
    (2016) Baudrand Biggs, René; Guarda Vega, Francisco; Torrey, J.; Williams, G.; Vaidya, A.
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    El tejido graso como modulador endocrino: cambios hormonales asociados a la obesidad
    (2010) Baudrand Biggs, René; Arteaga U., Eugenio; Moreno González, Manuel I.
    Adipose tissue not only stores fat, but secretes factors and hormones, which modify the regulation, metabolism and secretion of several other hormones. The objective of this review is to describe the hormonal disorders associated with increased adipose tissue, which acts as a modulator or disruptor of the endocrine physiology, with special reference to cortisol, androgens, growth hormone and thyroid axis, and discuss the implications for the management and treatment of these patients.
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    High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome
    (2014) Baudrand Biggs, René; Campino Johnson, María del Carmen; Carvajal Maldonado, Cristián Andrés; Olivieri, O.; Guidi, G.; Faccini, G.; Vöhringer, P.A.; Cerda, Jaime; Owen, Gareth Ivor; Kalergis Parra, Alexis Mikes; Fardella B., Carlos