Browsing by Author "Barros, Eric R."

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    Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles
    (2021) Blijdorp, Charles J.; Tutakhel, Omar A. Z.; Hartjes, Thomas A.; van den Bosch, Thierry P. P.; van Heugten, Martijn H.; Rigalli, Juan Pablo; Willemsen, Rob; Musterd-Bhaggoe, Usha M.; Barros, Eric R.; Carles-Fontana, Roger; Carvajal, Cristian A.; Arntz, Onno J.; van de Loo, Fons A. J.; Jenster, Guido; Clahsen-van Groningen, Marian C.; Cuevas, Cathy A.; Severs, David; Fenton, Robert A.; van Royen, Martin E.; Hoenderop, Joost G. J.; Bindels, Rene J. M.; Hoorn, Ewout J.
    Background: Urinary extracellular vesicles (uEVs) are a promising source for biomarker discovery, but optimal approaches for normalization, quantification, and characterization in spot urines are unclear.
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    Proteomic Profile of Urinary Extracellular Vesicles Identifies AGP1 as a Potential Biomarker of Primary Aldosteronism
    (2021) Barros, Eric R.; Rigalli, Juan Pablo; Tapia-Castillo, Alejandra; Vecchiola, Andrea; Young, Morag J.; Hoenderop, Joost G. J.; Bindels, Rene J. M.; Fardella, Carlos E.; Carvajal, Cristian A.
    Context: Primary aldosteronism (PA) represents 6% to 10% of all essential hypertension patients and is diagnosed using the aldosterone-to-renin ratio (ARR) and confirmatory studies. The complexity of PA diagnosis encourages the identification of novel PA biomarkers. Urinary extracellular vesicles (uEVs) are a potential source of biomarkers, considering that their cargo reflects the content of the parent cell.