Browsing by Author "Arteaga, Pilar"

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    Mild and rapid method for the generation of o-quinone methide intermediates.: Synthesis of puupehedione analogues
    (2006) Barrero, Alejandro F.; del Moral, Jose F. Quilez; Herrador, M. Mar; Arteaga, Pilar; Cortes, Manuel; Benites, Julio; Rosellon, Antonio
    A route to simpler analogues to bioactive puupehedione derivatives involving a hetero Diels-Alder cycloaddition of a o-quinone methide is described. These intermediate species are generated via fluoride-induced desilylation of silyl derivatives of o-hydroxybenzyl iodides. Remarkable short reaction times and very mild experimental conditions are the main features of this method. (c) 2006 Elsevier Ltd. All rights reserved.
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    Solid-phase selenium-catalyzed selective allylic chlorination of polyprenoids
    (2006) Barrero, Alejandro F.; Quilez del Moral, Jose F.; Mar Herrador, M.; Cortes, Manuel; Arteaga, Pilar; Catalan, Julieta V.; Sanchez, Elena M.; Arteaga, Jesus F.
    Regioselective halogenation of the terminal isopropylidene unit of different acyclic polyolefinic polyprenoids (farnesyl acetate, geranylgeranyl acetate, squalene, etc.) using NCS/ catalytic polymer-supported selenenyl bromide is described; good to excellent yields are obtained (68-96%). The first applications of this protocol include the concise synthesis of bioactive terpenoids 1-3.