Browsing by Author "Arias-Carrasco R."

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    Novel molecular insights and public omics data in pulmonary hypertension
    (Elsevier B.V., 2021) Lopez-Crisosto C.; Arias-Carrasco R.; Maracaja-Coutinho V.; Lavandero S.; Lopez-Crisosto C.; Sepulveda P.; Verdejo H.E.; Castro P.F.; Sepulveda P.; Verdejo H.E.; Castro P.F.; Garrido-Olivares L.; Lavandero S.
    © 2021 Elsevier B.V.Pulmonary hypertension is a rare disease with high morbidity and mortality which mainly affects women of reproductive age. Despite recent advances in understanding the pathogenesis of pulmonary hypertension, the high heterogeneity in the presentation of the disease among different patients makes it difficult to make an accurate diagnosis and to apply this knowledge to effective treatments. Therefore, new studies are required to focus on translational and personalized medicine to overcome the lack of specificity and efficacy of current management. Here, we review the majority of public databases storing ‘omics’ data of pulmonary hypertension studies, from animal models to human patients. Moreover, we review some of the new molecular mechanisms involved in the pathogenesis of pulmonary hypertension, including non-coding RNAs and the application of ‘omics’ data to understand this pathology, hoping that these new approaches will provide insights to guide the way to personalized diagnosis and treatment.
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    Publisher Correction: Bacterial networks in Atlantic salmon with Piscirickettsiosis (Scientific Reports, (2023), 13, 1, (17321), 10.1038/s41598-023-43345-x)
    (2023) Coca Y.; Godoy M.; Pontigo J.P.; Caro D.; Maracaja-Coutinho V.; Arias-Carrasco R.; Rodriguez-Cordova L.; de Oca M.M.; Saez-Navarrete C.; Burbulis I.
    © 2023, The Author(s).In the original version of this Article, Affiliation 6 and 11 were not listed in the correct order. The correct affiliations are listed below: 6Programa Institucional de Fomento a la Investigación, Desarrollo e Innovación (PIDi), Universidad Tecnológica Metropolitana, Avenida Dieciocho 161, 8330383 Santiago, Región Metropolitana, Chile. 7Facultad de Ingeniería, Escuela de Ingeniería, Universidad Santo Tomás, Avenida Ejército Libertador 146, Santiago, Región Metropolitana, Chile. 8Departamento de Ingeniería Química y Bioprocesos, Pontificia Universidad Católica de Chile, Avenida Vicuña Mackenna 4860, 7820436 Santiago, Región Metropolitana, Chile. 9Centro de Investigación en Nanotecnología y Materiales Avanzados (CIEN-UC), Pontificia Universidad Católica de Chile, Avenida Vicuña Mackenna 4860, 7820436 Santiago, Región Metropolitana, Chile. 10Centro de Investigación Biomédica, Facultad de Medicina y Ciencia, Universidad San Sebastián, Sede Patagonia, Avenida Lago Panguipulli 1390, Puerto Montt, Región de Los Lagos, Chile. 11Unidad de Genómica Avanzada, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Avenida Dr. Carlos Lorca Tobar 964, 8380494 Santiago, Región Metropolitana, Chile. The original Article has been corrected.