Browsing by Author "Andresen M."

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    Brain injuries from fisting. Front impact model
    (Springer, 2023) Ponce E.; Ponce D.; Andresen M.; Ponce M.; Barrio L.; Leon D.; CEDEUS (Chile)
    © 2023, Universidad Autonoma de Madrid y CV Ciencias del Deporte. All rights reserved.Boxing and other combat sports are associated with repetitive head trauma related to damage to the central nervous system. This work aimed to model the effect of a punch to the forehead given by a heavyweight boxer. Methodology: the Finite Element Method (FEM) was used. The research was based on simulating the effects of a dynamic impact and thus predicting, locating, and quantifying changes in the brain due to the blow. This simulation was validated by comparing medical research on brain injuries caused by impacts to the head. Results: The mathematical predictions showed significant brain effects: figures that exceed 100% risk. The MEF appears to be a practical, universal, inexpensive, and quick calculation tool, with important applications to detect evidence of brain trauma.
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    Neurology and COVID-19: Case series of neurological complications in 96 patients admitted at a university hospitalNeurología hospitalaria y COVID-19: serie de 96 pacientes evaluados en un hospital universitario
    (Academic Press, 2021) Godoy-Santín J.; Aguilar C.; Gutiérrez D.; Miranda H.; Rubio P.S.; Mellado P.; Grau S.B.; Andresen M.; Godoy-Santín J.; Nuñez F.; Ramos B.; Lorena G.A.
    © 2021 Sociedad Medica de Santiago. All rights reserved.Background: There are multisystemic consequences secondary to SARSCoV- 2 infection. Aim: To characterize neurological complications in patients admitted due to SARS-CoV-2 infection. Methods: Review of medical records of patients aged over 15 years with COVID-19 evaluated by the neurology team between April and August 2020 at a university hospital. Severity of the infection, referral reasons, neurological diagnoses and laboratory results were registered. The diagnoses were defined by consensus among the members of the hospital neurology group. Cerebrovascular and inflammatory diseases of the central and peripheral nervous system were defined as "probably associated" or "possibly associated" to COVID-19. Results: Ninety-six patients had at least 1 new neurological complication. 74% were admitted due to pneumonia and 20% due to a neurological disease. The most common reasons for neurological referral were impaired consciousness (39%), focal neurological deficit (24%), headache (9%) and seizures (5%). The most relevant neurological diagnoses were delirium in 48 patients, stroke in 24, critical illness polyneuropathy and myopathy in 17, seizures in 14, brachial plexopathy in 3, compressive neuropathies in 5, encephalitis in 1, possible vasculitis in 1 and Guillain-Barré syndrome in 1. Stroke and epilepsy were associated with increased length of hospital stay, but without differences in mortality. Conclusions: The spectrum of neurological complications of COVID-19 is wide. There are clinical entities typical of critically ill patients and also diseases associated directly and indirectly with the SARS-CoV2 infection.
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    Risk factors for adverse drug reactions in patients admitted to intensive care unitsDeterminación de factores de riesgo a reacciones adversas a medicamentos mediante farmacovigilancia intensiva en UCI
    (HUMANA PRESS INC, 2021) Obreque K.; Mellado R.; Andresen M.
    © 2021 Sociedad Medica de Santiago. All rights reserved.Background: Patients hospitalized in intensive care units (ICU) are at higher risk of having adverse drug reactions (ADR). Aim: To determine risk factors for ADR, through intensive pharmacological surveillance at the ICU. Patients and Methods: An observational, descriptive and prospective study was made, determining risk parameters in patients who experienced ADR. Results: Eighty-five patients were surveilled and 24 (28%) had an ADR. A total of 48 drugs responsible for at least one ADR were identified. Seventy-three percent ADR were moderate and 27% were severe. The clinical variables significantly associated with ADR were a history of allergies, a high body mass index, the reason for admission, an APACHE II score ≥ 14 points, the use of invasive mechanical ventilation and more than seven days of hospitalization. The pharmacological variables associated with ADR were polypharmacy and medication associations and combinations. Conclusions: The identified risk factors have a great impact on pharmacokinetic and pharmacodynamic parameters, and should be considered to avoid the appearance of ADR.
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    Severe metabolic disorder associated with an enterovesical fistula. Report of one caseTrastorno grave del medio interno por fistula enterovesical, a proposito de un caso clinico
    (2022) Avila E.; Sepulveda R.A.; Ruedi C.; Munoz F.; Andresen M.
    © 2022 Sociedad Medica de Santiago. All rights reserved.Enterovesical fistula (EVF) is a fistulous communication between the intestine and the bladder. It is uncommon and its classic clinical manifestations are the presence of pneumaturia, fecaluria, suprapubic pain and recurrent urinary infections. Surgical repair of EVF leads to rapid correction of both diarrhea and metabolic abnormalities. We report a 73-year-old diabetic woman with a neurogenic bladder secondary to a spine meningioma. She presented with diarrhea, vomiting, impaired consciousness and metabolic acidosis. She developed hypernatremia, hypokalemia, hypocalcemia, and hypophosphatemia, which were successfully corrected.