Browsing by Author "Aleissa, S."
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- ItemDermoscopy and reflectance confocal microscopy of intraepidermal Merkel cell carcinoma(2020) Navarrete Dechent, Cristián Patricio; Córdova, M.; Aleissa, S.; Battle, L. R.; Ganly, I.; Pulitzer, M.; Rossi, A. M.
- ItemIncompletely excised lentigo maligna melanoma is associated with unpredictable residual disease: clinical features and the emerging role of reflectance confocal microscopy(2020) Navarrete-Dechent, C.; Aleissa, S.; Cordova, M.; Liopyris, K.; Lee, E. H.; Rossi, A. M.; Hollman, T.; Pulitzer, M.; Lezcano, C.; Busam, K. J.; Marghoob, A. A.; Chen, C-C J.; Nehal, K. S.Background Lentigo maligna/lentigo maligna melanoma (LM/LMM) poses a treatment and surgical challenge given unpredictable subclinical extension resulting in incomplete excision. Objectives To describe the demographic, clinical and pathologic characteristics of incompletely excisedLM/LMM. To evaluate the potential role of reflectance confocal microscopy (RCM). Patients and methods A retrospective review of a melanoma database at a tertiary cancer centre for patients referred with 'incompletely excisedLM/LMM' or 'incompletely excised melanoma' between October 2006 and July 2017. We recorded clinical and pathological data and surgical margins needed to clear the residualLM/LMM. The second part consisted of a prospective cohort of patients in whichRCMwas performed when presenting with incompletely excisedLM/LMM. Results We included a total of 67 patients (retrospective + prospective cohort); mean age was 64.9 (standard deviation: 11.3) years and 52.2% were males. For the retrospective cohort (n = 53), the mean scar size was 3.4 cm. The average initial margins excised prior to presentation were 4.8 mm (range 3-7 mm). The average additional margin needed to clear the residual, incompletely excisedLM/LMMwas 7.8 mm. For the prospective cohort (n = 14), there were no differences in age, gender or size when compared to the retrospective cohort.RCMhad a diagnostic accuracy of 78.6%, a sensitivity of 90.9%, a specificity of 33.3% and a positive predictive value of 83.3% for the detection of incompletely excisedLM/LMM. Conclusions Incompletely excisedLM/LMMis a poorly characterized clinical-pathological scenario that may require considerable extra margins for microscopic clearance.RCMmay emerge as a valuable tool for the evaluation of patients with incompletely excisedLM/LMM.
- ItemManagement of complex head-and-neck basal cell carcinomas using a combined reflectance confocal microscopy/optical coherence tomography : a descriptive study(2020) Navarrete Dechent, Cristián Patricio; Aleissa, S.; Cordova, M.; Liopyris, K.; Sahu, A.; Rossi, A. M.; Lee, E. H.; Nehal, K. S.
- ItemPresurgical evaluation of basal cell carcinoma using combined reflectance confocal microscopy-optical coherence tomography : A prospective study(2020) Aleissa, S.; Navarrete Dechent, Cristián Patricio; Cordova, M.; Sahu, A.; Dusza, S. W.; Phillips, W.; Rossi, A.; Lee, E.; Nehal, K. S.
- ItemReflectance confocal microscopy and dermoscopy aid in evaluating repigmentation within or adjacent to lentigo maligna melanoma surgical scars(2020) Navarrete Dechent, Cristián Patricio; Cordova, M.; Liopyris, K.; Rishpon, A.; Aleissa, S.; Rossi, A.M.; Lee, E.; Chen, C.C.J.; Busam, K.J.; Marghoob, A.A.; Nehal, K.S.
- ItemReflectance confocal microscopy confirms residual basal cell carcinoma on clinically negative biopsy sites before Mohs micrographic surgery : a prospective study(2019) Navarrete Dechent, Cristián Patricio; Córdova, M.; Aleissa, S.; Liopyris, K.; Dusza, S. W.; Phillips, W.; Rossi, A. M.; Lee, E. H.; Marghoob, A. A.; Nehal, K. S.
- ItemReflectance confocal microscopy-guided carbon dioxide laser ablation of low-risk basal cell carcinomas : a prospective study(2019) Navarrete Dechent, Cristián Patricio; Córdova, M.; Liopyris, K.; Yelamos, O.; Aleissa, S.; Hibler, B.; Sierra, H.; Sahu, A.; Blank, N.; Rajadhyaksha, M.; Rossi, A.
- ItemSquamous cell carcinoma in situ upstaging is not frequent in the nail unit : a tertiary cancer center experience(2020) Aleissa, S.; Cowen, E.; Navarrete Dechent, Cristián Patricio; Busam, K. J.; Rossi, A. M.; Lee, E. H.; Nehal, K. S.
- ItemUse of paper tape to guide reflectance confocal microscopy navigation of large skin lesions(2020) Navarrete Dechent, Cristián Patricio; Cordova, M.; Aleissa, S.; Kose, K.; Lee, E. H.; Rossi, A. M.; Nehal, K. S.