Browsing by Author "Aguirre, J."
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- ItemA new multiplex PCR assay for the simultaneous detection of vancomycin-resistant enterococci from rectal swabs(2010) Benadof, D.; San Martín, M.; Aguirre, J.; Paredes, L.; Malig, R.; Melo Ledermann, Francisco Javier; Lehouque, G.Objectives This study describes the diagnostic performance of a recently available multiplex PCR-based kit for the simultaneous detection and identification of Enterococcus faecium, Enterococcus faecalis, vanA, vanB, vanC1 and vanC2/C3 genes, directly from rectal swabs constituting the most complete existing molecular assay currently available. Methods The diagnostic performance of this assay was evaluated by a multicenter study involving three independent public hospitals and consisted in the analysis of 187 rectal swabs from patients at high risk for vancomycin-resistant enterococci colonization. Results When bacteria culture was used as the gold standard, the sensitivity, specificity, positive and negative predicted values for the assay were 96.8%, 76.0%, 67.7% and 97.9%, respectively. When a composite reference standard consisting of culture and DNA sequencing of PCR products was used as the gold standard, the sensitivity, specificity, positive and negative predicted values for the PCR-based assay were 97.8%, 96.9%, 96.7% and 97.9%, respectively. Conclusions Based on these results, we conclude that this assay is considerably more sensitive than traditional microbiological methods for detecting vancomycin-resistant enterococci from rectal swabs. It is also much faster than culture. We believe that the implementation of this assay in routine clinical laboratories could help to reduce hospital-acquired vancomycin-resistant enterococci infections.
- ItemAnti-N-methyl-D-aspartate receptor and anti-ribosomal-P autoantibodies contribute to cognitive dysfunction in systemic lupus erythematosus(2015) Massardo Vega, Loreto; Bravo Zehnder, Marcela; Calderón, J.; Flores, P.; Padilla Pérez, Oslando; Aguirre, J.; Scoriels, L.; González, A.
- ItemCorrosion behavior of stainless steel AISI 470 in pacific seawater(2015) Aguirre, J.; Walczak, M.; Armijo, F.; Daille, L.; Fischer, D.; Galarce, C.; De La Iglesia, R.; Pizarro, G.; Vargas Cucurella, Ignacio Tomas
- ItemDamage potential reduction of optimally passive-controlled nonlinear structures(2015) Aguirre, J.; Almazán Campillay, José Luis
- ItemEffect of dissolved copper ions on erosion-corrosion synergy of X65 steel in simulated copper tailing slurry(2017) Aguirre, J.; Walczak, Magdalena
- ItemImpact of cognitive impairment, depression, disease activity, and disease damage on quality of life in women with systemic lupus erythematosus(2017) Calderón, J.; Flores, P.; Aguirre, J.; Valdivia Cabrera, Gonzalo; Padilla, O.; Barra, I.; Iscoriels, L.; Herrera, S.; González Arellano, Alejandro; Massardo Vega, Loreto
- ItemOptimal control of linear and nonlinear asymmetric structures by means of passive energy dampers(2013) Aguirre, J.; Almazán Campillay, José Luis; Paul, C.
- ItemPoly(3,4-ethylenedioxythiophene) used as a coating on stainless steel AISI 470. Evaluation of corrosion inhibition performance(2015) Aguirre, J.; Armijo, F.; Walczak, M.; De La Iglesia, R.; Pizarro, G.; Vargas Cucurella, Ignacio Tomas
- ItemThe Simons Observatory : science goals and forecasts(2019) Ade, P,; Aguirre, J.; Ahmed, Z.; Aiola, S.; Ali, A.; Alonso, D.; Alvarez, M.A.; Boettger, David; Maurin, Loïc Benjamin; Fluxá Rojas, Pedro Antonio