Browsing by Author "ARTEAGA, A"
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- ItemCHOLESTEROL DISTRIBUTION AMONG LIPOPROTEIN FRACTIONS IN PATIENTS WITH GOUT AND NORMAL CONTROLS(1986) JACOBELLI, S; ARTEAGA, A; BIDEGAIN, FThe relationship between gout and coronary disease is controversial. We studied the distribution of cholesterol among lipoprotein fractions separated by ultracentrifugation in a group of 29 gouty men and 34 healthy controls, matched by age, weight and serum glucose. Our results showed that patients had significantly higher serum triglycerides and cholesterol-VLDL and lower total cholesterol and cholesterol in LDL and HDL fractions. The comparison of both groups separated by weight and alcohol intake showed similar results. The cholesterol-LDL/cholesterol-HDL ratio was not significantly different between the groups. Based on these results, we conclude that our group of gouty patients may not be at greater risk of coronary disease than a similar control population.
- ItemCOMPLICATIONS AND OUTCOME OF PREGNANCY IN OBESE WOMEN(1989) TILTON, Z; HODGSON, MI; DONOSO, E; ARTEAGA, A; ROSSO, P
- ItemINFLUENCE OF LEGUME INTAKE ON BILIARY LIPIDS AND CHOLESTEROL SATURATION IN YOUNG CHILEAN MEN - IDENTIFICATION OF A DIETARY RISK FACTOR FOR CHOLESTEROL GALLSTONE FORMATION IN A HIGHLY PREVALENT AREA(1989) NERVI, F; COVARRUBIAS, C; BRAVO, P; VELASCO, N; ULLOA, N; CRUZ, F; FAVA, M; SEVERIN, C; DELPOZO, R; ANTEZANA, C; VALDIVIESO, V; ARTEAGA, AChileans and North American Indians have one of the highest prevalence rates of cholesterol gallstones in the world. The most common theory to explain this has been the operation of some as yet undefined genetic risk factor in these populations. Searching for some common environmental factor for gallstones in Chileans and North American Indians, we found that beans and other legumes are common foods consumed by both populations. In this study we tested the hypothesis that legume intake may favor the production of biliary cholesterol supersaturation. We studied 20 young men subjected to a diet containing 120 g/day of legumes and a control diet without legumes for a period of 1 mo each. Both diets supplied identical quantities of energy, carbohydrates, protein, total fat, fiber, and cholesterol. Low-density lipoprotein cholesterol concentration decreased by 16% (p < 0.001) after the legume diet. Biliary cholesterol saturation increased in 19 of the 20 subjects; the mean of the group markedly increased from 110% to 169% (p < 0.001) after the legume diet. These results are consistent with the hypothesis that legume intake is a potential risk factor for cholesterol gallstone disease.