Browsing by Author "AGUAYO, J"

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    DEVELOPMENT OF ANTI-HUMAN-B BLOOD GROUP MONOCLONAL-ANTIBODIES SUITABLE AS A BLOOD TYPING REAGENT
    (1994) BECKER, MI; JUICA, F; JAMETT, A; TZICHINOVSKY, S; BARROS, S; AGUAYO, J; DEIOANNES, AE
    An improved procedure for the generation of high-avidity anti-human B blood group monoclonal antibodies (MAbs) was developed. One of them, termed 7A1-2, showed excellent qualities of titer, avidity, and intensity required For use as human B blood typing reagent. Hemagglutination inhibition studies with monosaccharides and oligosaccharides were carried out to determine the specificity of the MAb 7A1-2. These studies indicate that the antibody reacts with the immunodominant region of the antigen which is known to confer the serologic specificity of this blood group.